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MX1
Другие языки:
MX1
Подписчиков: 0, рейтинг: 0
MX dynamin like GTPase 1 | |||||||
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المعرفات | |||||||
الأسماء المستعارة | interferon-induced protein p78, myxoma resistance protein 1, Myxovirus resistance protein 1, interferon-regulated resistance GTP-binding protein MxA, IFI-78K, interferon-inducible protein p78, myxovirus (influenza virus) resistance 1, interferon-inducible protein p78, MX1, interferon-induced GTP-binding protein Mx1 | ||||||
معرفات خارجية | |||||||
أورثولوج | |||||||
الأنواع | الإنسان | الفأر | |||||
أنتريه | n/a | ||||||
Ensembl | n/a | n/a | |||||
يونيبروت |
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RefSeq (مرسال ر.ن.ا.) |
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RefSeq (بروتين) |
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الموقع (UCSC | n/a | ||||||
بحث ببمد | n/a | ||||||
ويكي بيانات | |||||||
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MX1 (MX dynamin like GTPase 1) هوَ بروتين يُشَفر بواسطة جين MX1 في الإنسان.
الوظيفة
الأهمية السريرية
المراجع
قراءة متعمقة
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- Horisberger MA، McMaster GK، Zeller H، وآخرون (1990). "Cloning and sequence analyses of cDNAs for interferon- and virus-induced human Mx proteins reveal that they contain putative guanine nucleotide-binding sites: functional study of the corresponding gene promoter". J. Virol. ج. 64 ع. 3: 1171–81. PMC 249231. PMID 2154602.
- Pavlovic J، Zürcher T، Haller O، Staeheli P (1990). "Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein". J. Virol. ج. 64 ع. 7: 3370–5. PMC 249583. PMID 2161946.
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- Weitz G، Bekisz J، Zoon K، Arnheiter H (1990). "Purification and characterization of a human Mx protein". J. Interferon Res. ج. 9 ع. 6: 679–89. doi:10.1089/jir.1989.9.679. PMID 2607176.
- Maruyama K، Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. ج. 138 ع. 1–2: 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Melén K، Keskinen P، Ronni T، وآخرون (1996). "Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope". J. Biol. Chem. ج. 271 ع. 38: 23478–86. doi:10.1074/jbc.271.38.23478. PMID 8798556.
- Ponten A، Sick C، Weeber M، وآخرون (1997). "Dominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activity". J. Virol. ج. 71 ع. 4: 2591–9. PMC 191379. PMID 9060610.
- Fernández M، Quiroga JA، Martín J، وآخرون (1997). "Impaired interferon induction of human MxA protein in chronic hepatitis B virus infection". J. Med. Virol. ج. 51 ع. 4: 332–7. doi:10.1002/(SICI)1096-9071(199704)51:4<332::AID-JMV12>3.0.CO;2-K. PMID 9093949.
- Suzuki Y، Yoshitomo-Nakagawa K، Maruyama K، وآخرون (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. ج. 200 ع. 1–2: 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Li Y، Youssoufian H (1998). "MxA overexpression reveals a common genetic link in four Fanconi anemia complementation groups". J. Clin. Invest. ج. 100 ع. 11: 2873–80. doi:10.1172/JCI119836. PMC 508494. PMID 9389754.
- Kochs G، Trost M، Janzen C، Haller O (1998). "MxA GTPase: oligomerization and GTP-dependent interaction with viral RNP target structures". Methods. ج. 15 ع. 3: 255–63. doi:10.1006/meth.1998.0629. PMID 9735310.
- Weber F، Haller O، Kochs G (2000). "MxA GTPase blocks reporter gene expression of reconstituted Thogoto virus ribonucleoprotein complexes". J. Virol. ج. 74 ع. 1: 560–3. doi:10.1128/JVI.74.1.560-563.2000. PMC 111572. PMID 10590150.
- Hattori M، Fujiyama A، Taylor TD، وآخرون (2000). "The DNA sequence of human chromosome 21". Nature. ج. 405 ع. 6784: 311–9. doi:10.1038/35012518. PMID 10830953.
- Hijikata M، Ohta Y، Mishiro S (2000). "Identification of a single nucleotide polymorphism in the MxA gene promoter (G/T at nt -88) correlated with the response of hepatitis C patients to interferon". Intervirology. ج. 43 ع. 2: 124–7. doi:10.1159/000025035. PMID 10971132.
- Engelhardt OG، Ullrich E، Kochs G، Haller O (2002). "Interferon-induced antiviral Mx1 GTPase is associated with components of the SUMO-1 system and promyelocytic leukemia protein nuclear bodies". Exp. Cell Res. ج. 271 ع. 2: 286–95. doi:10.1006/excr.2001.5380. PMID 11716541.
- Hijikata M، Mishiro S، Miyamoto C، وآخرون (2002). "Genetic polymorphism of the MxA gene promoter and interferon responsiveness of hepatitis C patients: revisited by analyzing two SNP sites (-123 and -88) in vivo and in vitro". Intervirology. ج. 44 ع. 6: 379–82. doi:10.1159/000050075. PMID 11805446.
- Kochs G، Haener M، Aebi U، Haller O (2002). "Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers". J. Biol. Chem. ج. 277 ع. 16: 14172–6. doi:10.1074/jbc.M200244200. PMID 11847228.